Octopus: Optimal Clinical Trials Platform for Multiple Sclerosis
This is a revolutionary trial that will transform the way we test treatments for Progressive Multiple Sclerosis (MS). A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster.
Octopus is open to recruitment!
Platypus, the Australian extension of the trial will be opening up soon.
If you are a potential participant or a family member looking for more information about Octopus, visit the For Participants page.
If you're interested in the trial and would like to see if you are eligible, complete the Registration of Interest form.
You can explore which Trial sites are open at the Octopus Sites page.
To read about Trial news, visit the Publications and news page.
For more information on MS research and practical support for MS, visit the MS Society website.
We apologise that the trial team who oversee this website are unable to advise on eligibility and clinical queries.
If you would like to register your interest in the trial you can contact your MS nurse or complete a Registration of Interest form.
Register your Interest in Octopus
News:
Octopus has now opened in Australia!
Our first Australian site has just opened at Griffith University, Gold Coast, Australia.
The site have already recruited their first participant in October 2025.
In Australia, the trial is called “PLATYPUS, the Australian extension of Octopus”.
Octopus has hit a major milestone - over 500 participants randomised!
Learn how we and the MS Register look after your data.
I have MS and I would like to find out more
Click on the images below to find out more about each of these topics
About Octopus
Find out more about the design of the Octopus trial and who it is for.
About MAMS trials
In this section we focus on what a Multi-Arm Multi-Stage (MAMS) trial is, and why it can help research into MS.
Register Your Interest
I would like to register my interest in Octopus. What do I do next?
Participant Information Sheet
Access the Octopus Participant Information Sheet.
Frequently Asked Questions (FAQs)
We have put together some of the most frequently asked questions about the trial.
Octopus is funded by the MS Society with supported funding from MS Australia and MSWA for the Australian extension Platypus
