Participant Information Sheet

From left to right: trial participant Ailsa Guidi, her partner Rob Guidi, and trial physician Dr Sean Mangion. Image courtesy of the MS Society

You can find more information about the Octopus trial in the Participant Information Sheet (version 5.0) for participants who joined in Analysis stage 1 and Participant Information Sheet for stage 2 from the 27th November or you can read the Octopus Visit Information Sheet (version 3.0).

Please note: these documents are for information only. Participants going through the recruitment process will be given the Participant Information Sheet specific to their trial site (highlighted in yellow in the "Participant Information Sheet" pdf).

We have also put together a video to support the Participant Information Sheet. This is supplementary to the Participant Information Sheet, and designed to be used alongside it to help you and help decide whether you wish to take part.

The film features Jeremy Chataway, Chief Investigator of the Octopus trial and Professor of Neurology at the National Hospital for Neurology and Neurosurgery, part of the University College London Hospitals NHS Foundation Trust.

See below the video and time stamp so you can skip to specific chapters:

00:00 - Intro

00:30 - What is multiple sclerosis (MS)?

01:11 - What is the aim of the Octopus trial?

02:48 - Who can take part in the Octopus trial?

03:18 - What happens in a clinical trial that has a placebo or dummy drug?

04:06 - What is randomisation in a clinical trial?

04:51 - What happens in the first stage of the Octopus trial?

05:56 - What happens if the Octopus treatment does not show benefit?

06:35 - What happens if the Octopus treatment does show benefit?

07:09 - How have people with MS shaped the Octopus trial?

07:31 - Further information